Psoriasis is a chronic inflammatory condition with recognized micro and macrovascular complication. Inflammation along with platelet activation plays the main role in psoriasis. MPV, NLR and PLR are the proven biomarkers of inflammation and platelet activation. Cardiovascular and thrombotic risk can be minimized with early recognition and prevention. These three markers are cheap ,convenient and easily accessible even in the rural area.Zaheer et al (2015) showed that MPV was higher in psoriasis patient in relation to healthy individual in a case control study of total 60 subjects.
MPV shows significantly higher in psoriasis patient in comparison to the healthy individuals by using independent sample t test. The mean value of MPV in psoriasis patients group was 8.24±1.22 fl Where as in helathy individuals of the control group it was 7.29±0.
Best services for writing your paper according to Trustpilot
77 fl. P value was significant (P=0.001), when comparison of means of MPV in both group was observed. Investigator concluded as this abnormal morphology along with increased platelet activation ultimately results of long term micro and macro vascular complication of this disease, MPV-a simple cost effective test which can identify risk of cardiovascular diseases, can be used as a tool to start early preventive measure.
